机读格式显示(MARC)

• 000 03117cam a2200397 a 4500

• 001 0000852380

• 003 CAL

• 005 20101210154440.8

• 008 100203s2010 njua b 001 0 eng

• 010 __ |a 2010003433

• 020 __ |a 9780470479964 (cloth)

• 040 __ |a DNLM/DLC |c DLC |d YDX |d NLM |d BTCTA |d YDXCP |d CDX |d DLC

• 042 __ |a pcc

• 050 00 |a RA762 |b .S58 2010

• 082 00 |a 610.28/4 |2 22

• 093 __ |a TH773 |2 4

• 099 __ |a CAL 022010260089

• 100 1_ |a Shunmugaperumal, Tamilvanan.

• 245 10 |a Biofilm eradication and prevention : |b a pharmaceutical approach to medical device infections / |c Tamilvanan Shunmugaperumal.

• 260 __ |a Hoboken, N.J. : |b Wiley, |c c2010.

• 300 __ |a xiii, 423 p. : |b ill. ; |c 25 cm.

• 504 __ |a Includes bibliographical references and index.

• 505 0_ |a (Publisher-supplied data) Chapter 1. Introduction and Overview of Biofilm Chapter 2. Rationale for biofilm eradication from modern medical devices Chapter 3. Pathogenesis of device-related nosocomial infections Chapter 4. Biofilm resistance/tolerance to conventional antimicrobial agents Chapter 5. Analytical techniques useful to study biofilm Chapter 6. Biofilm-related infections in ophthalmology Chapter 7. Biofilm-related infections in oral cavity Chapter 8. Implications of biofilm formation in chronic wound and in cystic fibrosis Chapter 9. Strategies for prevention of device-related nosocomial infections Chapter 10. Liposomes as drug delivery carriers to biofilms Chapter 11. Polymer-based antimicrobial delivery carriers.

• 520 __ |a "Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation"--Provided by publisher.

• 650 _0 |a Medical instruments and apparatus |x Microbiology.

• 650 _0 |a Biofilms.

• 650 _0 |a Medical instruments and apparatus |x Sterilization.

• 650 12 |a Biofilms.

• 650 22 |a Anti-Infective Agents |x therapeutic use.

• 650 22 |a Drug Carriers |x therapeutic use.

• 650 22 |a Prostheses and Implants |x microbiology.

• 650 22 |a Prosthesis-Related Infections |x prevention & control.

• 920 __ |a 244050 |z 2

• 920 __ |a F44010 |z 2

• 920 __ |a 244020 |z 2

• 998 __ |a SCT