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• 000 01951cam a2200337 a 4500

• 001 0000852264

• 003 CAL

• 005 20120210113417.4

• 008 101008s2011 njua b 001 0 eng

• 010 __ |a 2010043288

• 020 __ |a 9780470569061 (cloth)

• 020 __ |a 0470569069 (cloth)

• 040 __ |a DNLM/DLC |c DLC |d YDX |d NLM |d YDXCP |d DLC

• 050 00 |a RM301.5 |b .R655 2011

• 060 10 |a QV 38

• 082 00 |a 615/.7 |2 22

• 093 __ |a R969.1 |2 5

• 099 __ |a CAL 022012012926

• 100 1_ |a Rosenbaum, Sara |q (Sara E.)

• 245 10 |a Basic pharmacokinetics and pharmacodynamics : |b an integrated textbook and computer simulations / |c Sara Rosenbaum.

• 260 __ |a Hoboken, N.J. : |b John Wiley & Sons, |c c2011.

• 300 __ |a xviii, 430 p. : |b ill. ; |c 26 cm.

• 504 __ |a Includes bibliographical references and index.

• 505 0_ |a Introduction to pharmacokinetics and pharmacodynamics -- Passage of drug through membranes -- Drug absorption -- Drug elimination -- Compartmental models -- Pharmacokinetics of an intravenous bolus injection in a one compartment model -- An intravenous bolus injection in the two compartment model -- Pharmacokinetics of extravascular drug administration -- Introduction to non-compartmental analysis -- Pharmacokinetics of the intravenous infusion in a one compartment model -- Multiple intravenous bolus injections in the one compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacodynamic models and integrated pharmacokinetic- pharmacodynamics (PK-PD) models -- Mechanism based integrated pharmacokinetic-pharmacodynamic models.

• 650 _0 |a Pharmacokinetics |v Textbooks.

• 650 _0 |a Pharmacokinetics |x Computer simulation.

• 650 _0 |a Drugs |x Physiological effect |v Textbooks.

• 650 _0 |a Drugs |x Physiological effect |x Computer simulation.

• 650 12 |a Pharmacokinetics.

• 650 22 |a Computer Simulation.

• 650 22 |a Pharmacological Phenomena.