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- 题名/责任者:
- Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations / Sara Rosenbaum.
- 出版发行项:
- Hoboken, N.J. : John Wiley & Sons, c2011.
- ISBN:
- 9780470569061 (cloth)
- ISBN:
- 0470569069 (cloth)
- 载体形态项:
- xviii, 430 p. : ill. ; 26 cm.
- 个人责任者:
- Rosenbaum, Sara (Sara E.)
- 论题主题:
- Pharmacokinetics-Textbooks.
- 论题主题:
- Pharmacokinetics-Computer simulation.
- 论题主题:
- Drugs-Physiological effect-Textbooks.
- 论题主题:
- Drugs-Physiological effect-Computer simulation.
- 论题主题:
- Pharmacokinetics.
- 论题主题:
- Computer Simulation.
- 中图法分类号:
- R969.1
- 书目附注:
- Includes bibliographical references and index.
- 内容附注:
- Introduction to pharmacokinetics and pharmacodynamics -- Passage of drug through membranes -- Drug absorption -- Drug elimination -- Compartmental models -- Pharmacokinetics of an intravenous bolus injection in a one compartment model -- An intravenous bolus injection in the two compartment model -- Pharmacokinetics of extravascular drug administration -- Introduction to non-compartmental analysis -- Pharmacokinetics of the intravenous infusion in a one compartment model -- Multiple intravenous bolus injections in the one compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacodynamic models and integrated pharmacokinetic- pharmacodynamics (PK-PD) models -- Mechanism based integrated pharmacokinetic-pharmacodynamic models.
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