- 题名/责任者:
- Biofilm eradication and prevention : a pharmaceutical approach to medical device infections / Tamilvanan Shunmugaperumal.
- 出版发行项:
- Hoboken, N.J. : Wiley, c2010.
- ISBN:
- 9780470479964 (cloth)
- 载体形态项:
- xiii, 423 p. : ill. ; 25 cm.
- 个人责任者:
- Shunmugaperumal, Tamilvanan.
- 论题主题:
- Medical instruments and apparatus-Microbiology.
- 论题主题:
- Biofilms.
- 论题主题:
- Medical instruments and apparatus-Sterilization.
- 论题主题:
- Biofilms.
- 论题主题:
- Anti-Infective Agents-therapeutic use.
- 论题主题:
- Drug Carriers-therapeutic use.
- 论题主题:
- Prostheses and Implants-microbiology.
- 论题主题:
- Prosthesis-Related Infections-prevention & control.
- 中图法分类号:
- TH773
- 书目附注:
- Includes bibliographical references and index.
- 内容附注:
- (Publisher-supplied data) Chapter 1. Introduction and Overview of Biofilm Chapter 2. Rationale for biofilm eradication from modern medical devices Chapter 3. Pathogenesis of device-related nosocomial infections Chapter 4. Biofilm resistance/tolerance to conventional antimicrobial agents Chapter 5. Analytical techniques useful to study biofilm Chapter 6. Biofilm-related infections in ophthalmology Chapter 7. Biofilm-related infections in oral cavity Chapter 8. Implications of biofilm formation in chronic wound and in cystic fibrosis Chapter 9. Strategies for prevention of device-related nosocomial infections Chapter 10. Liposomes as drug delivery carriers to biofilms Chapter 11. Polymer-based antimicrobial delivery carriers.
- 摘要附注:
- "Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation"--Provided by publisher.
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